Thanks Bernard — The burgeoning 4E (Embodied, Extended, Enactive, Embedded) cognition perspective in psychology is a rich seam for exploring mind and brain as embedded and structured in interactions between humans and their environment. Weaving in and out of philosophy of mind, it offers new frames and directions for seeing and understanding the relational, dynamic nature of health/disease, forces and their affects. When you elevate this to the ecosystem level, novel explanations of “why?” and valid possibilities of “what to do?” emerge. 4E contrasts with the dominant reductionist, representational, mechanistic “mind separate from body” thinking in cognitive neuroscience — a paradigm that can never account for complexity, difference, formation, persistence, and especially the spatial and social intensities of disease and its experience over a duration.